Will Ferrell has replaced Iron Man star Robert Downey Jr. in Oobermind.

Father of six Brad Pitt and Superbad‘s Jonah Hill have also joined the voice cast of the forthcoming DreamWorks movie, which follows the titular character, an evil criminal mastermind—played by Will—who finds his life becomes dull when he defeats his rival, Brad’s Metro Man.

Jonah will voice Titan, a new superhero created by Oobermind while Tina Fey voices a reporter tracking the crime fighters.

Sherlock Holmes star Robert cited “scheduling conflicts” for his departure from the project, adding fuel to speculation he is to play the role of Lestat—made famous by Tom Cruise in Interview With The Vampire—in a new retelling of Anne Rice’s Vampire Chronicles novels.

Oobermind is scheduled for release in November 2010.